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Advanced Skin Recovery

Colsigen Refresh Collagen Sheet Mask

FDA Class I Medical DeviceHumanized Type III CollagenVegan20-minute mask ritual Fragrance-free Post-procedure care

A professional-grade sheet mask ritual featuring Humanized Type III Collagen to soothe, deeply hydrate and support skin after aesthetic procedures or whenever skin needs a focused recovery moment.

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$319.95Tax calculated at checkout.
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  • Suitable for sensitive, reactive, or post-treatment skin
  • Delivers soothing and deep hydration
  • Fragrance-free, so it won't irritate delicate or recovering skin
  • Helps support skin's moisture barrier and repair processes

Use Colsigen as a soothing and hydrating step when skin feels dry, tight, warm, sensitive, or in need of a simple post-treatment routine. Follow the product-specific usage guidance below and any instructions provided by your skincare professional.

Colsigen focuses on Humanized Type III Collagen with a concise support system. The products are fragrance-free and designed to soothe, deeply hydrate and support compromised or sensitive-feeling skin without unnecessary complexity.

Mask: 100% plant fiber.

Gel: Purified water, Glycerin, Recombinant type III Humanized Collagen, Carbomer, Methylparaben, Disodium EDTA, Triethanolamine.

Your Complete Routine

Product safety

Product Features

Thoughtfully designed to support sensitive and post-procedure skin.

VEGAN & FERMENTATION-DERIVEDProduced using advanced fermentation technology instead of animal-derived collagen for consistent quality.
DESIGNED FOR SENSITIVE SKIN AND POST-PROCEDURE SKINA streamlined formula designed to be gentle on sensitive and post-procedure skin.
FDA CLASS I MEDICAL DEVICERegistered as an FDA Class I Medical Device, meeting applicable regulatory requirements for its intended use.
Product Features

20-minute hydration ritual

Where Science Meets Skin Recovery

Where Science Meets Skin Recovery

Colsigen Formulation

Built around 3 core ingredients. One Advanced Formula.

Humanized Type III Collagen

Humanized Type III Collagen

Helps form a light protective film on the skin's surface.

Glycerin

Glycerin

Helps attract and retain moisture to support hydration.

Purified Water

Purified Water

Provides a lightweight, water-based vehicle for hydration support.

Application

How to apply?

Prepare and pre-hydrate
1

Prepare and pre-hydrate

Cleanse with lukewarm water. If desired, mist lightly with Colsigen Mist before the mask to help prepare the skin with a comfortable hydration layer.

Apply the mask gently
2

Apply the mask gently

Place Colsigen Refresh on clean, dry skin and smooth it into position without pulling. Use at room temperature.

Relax for 20 minutes
3

Relax for 20 minutes

Relax and enjoy for 20 minutes while mask is working.

Let Serum Absorb
4

Let Serum Absorb

Let remaining serum absorb naturally, then continue with Colsigen Mist and your usual skincare steps.

Application Tips

Tips to enhance the Colsigen routine

Use at room temperature or warm the unopened sachet in hands before application to enhance comfort.

Application video

See Colsigen Refresh in Action

See how easy it is to apply Colsigen Refresh for a relaxing 20-minute skincare treatment.

  • Apply to clean, dry skin
  • Leave on for 20 minutes
  • Gently remove and massage in any remaining serum
Colsigen clinical evidence visual

Week 12 skin-quality improvement

Day 10 - Signs and symptoms reduction

View Clinical Studies

Questions

Questions before you start

  • Patients’ post-cosmetic procedures (laser resurfacing, microdermabrasion, microneedling, superficial peels…)
  • Individuals with sensitive, dry, or stressed skin
  • Everyday use, for all skin types

Colsigen Refresh can be used daily or as needed. It is safe for regular use on all skin types.

Use Colsigen Refresh at room temperature or warm the unopened sachet in hands before application to enhance comfort.

Yes. Colsigen Refresh is designed for comfort-focused post-treatment routines such as laser, microneedling, peels, or microdermabrasion.

Yes. all Colsigen® products contains no animal-derived ingredients. The collagen is produced through recombinant biotechnology using a non-animal fermentation process.

View full FAQ


The Complete Post-Procedure Care Routine

A simple 3-step routine designed to help hydrate, comfort, and support skin repair after aesthetic procedures

  1. Spray Colsigen Mist to provide instant moisture support for skin
  2. Apply Colsigen Refresh to soothe and deeply hydrate skin
  3. Seal your routine with Stratacel® wound dressing gel for faster recovery
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