Relative reduction reported at Day 10.
Clinical efficacy
Clinical Efficacy
The evidence, expert insight, and ongoing research behind Colsigen.
Clinical efficacy
Clinical evidence after IPL treatment
A randomized controlled study of 120 patients compared Colsigen with a standard moisturising dressing after facial IPL photorejuvenation.
Signs and symptoms reduction
By Day 10, the Colsigen arm showed a significantly greater reduction in investigator-rated signs and symptoms scores versus the moisturiser arm.
Relative reduction reported at Day 10.
Largest absolute between-arm difference reported at Day 10.
Investigator-rated VAS, Day 10. Relative reduction equals between-arm difference as a proportion of the moisturiser score; all p < 0.05; Wilcoxon signed-rank test.
Skin quality improvement
At Week 12, the Colsigen arm showed greater improvement from baseline across the six reported skin-quality parameters.
Between-arm difference in improvement from baseline.
Between-arm difference in improvement from baseline.
Between-arm difference in improvement from baseline.
Between-arm difference in improvement from baseline, percentage points. Difference equals Colsigen minus moisturiser. TEWL = transepidermal water loss. Radiance: moisturiser declined 9.6%, Colsigen improved 13.1%.
White papers
Scientific White Papers
Approved scientific documents and study summaries for Colsigen.
AMWC CONGRESS
AMWC 2026 Workshop
A professional education section for congress recordings, speaker information, and workshop resources.
Advanced skin recovery: From procedure to repair
AMWC 2026 workshop content featuring Professor Leonardo Marini and Dr. Susanna Marini, presenting a practical two-step post-procedure recovery protocol with Colsigen and Stratacel following laser technology.
FOR HEALTHCARE PROFESSIONALS
Interested in Colsigen® samples?
Use the healthcare professional inquiries page to contact the Colsigen team.
Clinical perspectives
Doctor perspectives
"In my practice, I've found Colsigen to be a valuable addition for patients with sensitive or post-treatment skin looking to support skin comfort and repair. The Humanized Type III Collagen technology reflects the kind of science-backed formulation I look for when recommending skincare to my patients."
Dr. Michael H. Gold
"Colsigen® is the ideal solution to soothe and support the recovery of a disturbed skin barrier. An advanced, biocompatible companion that provides intensive hydration and supports skin repair."
Prof. Leonardo Marini