SCIENCE & TECHNOLOGY

Human-Sequence Type III Collagen

The science behind gentle, everyday skin recovery featuring Humanized Type III Collagen, an advanced biotechnology.

Humanized Type III Collagen science banner
100% human Type III sequence homology

Designed to match the amino acid sequence of native human Type III collagen.

Vegan controlled biotech manufacturing

Fermentation-derived production, non-animal and batch controlled.

High Purity compatible for all skin types

Manufactured under controlled conditions with defined purification and quality testing.

Skin repair foundation

Why Type III collagen matters in early wound healing

Type III collagen is the predominant collagen in granulation tissue during early wound healing, making it especially critical for post procedure recovery and skin repair. It provides structural support while the skin repairs itself and helps support the skin's natural recovery process. (1)

What it is

A bioengineered collagen designed to match human Type III collagen

Recombinant humanized Type III collagen is a bioengineered analogue of human Type III collagen produced using controlled biotechnology processes rather than animal extraction. It is designed to replicate the amino acid sequence and structural characteristics of human Type III collagen. The term humanized refers to this bioengineering similarity and does not imply human origin.(2)(3)

Made through controlled yeast fermentation

How it is made

Made through controlled yeast fermentation

Recombinant humanized Type III collagen is produced using a controlled yeast fermentation process. (4)

  1. The gene sequence encoding human Type III collagen is identified.
  2. The gene is introduced into a controlled yeast expression system (Pichia pastoris).
  3. The protein is produced through fermentation in a bioreactor.
  4. The material is purified and tested to verify quality and safety specifications.

Characteristics & benefits

  • Humanized collagen structure (4)
  • Biotechnology-derived production (4)
  • Defined purity and quality standards (4)
  • Non-animal source (4)

Questions

Colsigen FAQ

View all FAQs
A lab-engineered collagen protein designed to closely resemble human collagen, produced without animal-derived ingredients using recombinant DNA technology.
Yes, Colsigen® humanized Type III collagen has the exact same amino acid sequence (100% homology) as the Type III collagen naturally found in the human body—produced recombinantly via controlled fermentation for purity and safety.
Our formulations are based on biotechnology-derived, non-animal proteins to ensure consistency, safety, and ethical sourcing. This approach also minimizes the risk of immune reactions.
Not at all. Colsigen® is based on recombinant humanized type III collagen, bio-identical to what's naturally found in youthful human skin. Unlike collagen from animals, it offers precise compatibility, better bioavailability, and targeted skin regeneration.
Yes. Colsigen® contains no animal-derived ingredients. The collagen is produced through recombinant biotechnology using a non-animal fermentation process.